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Karver Laboratory (CSH-017)

Karver Laboratory is documented in the DePaul Resource Map as center at DePaul University, College of Science and Health, Chemistry and Biochemistry, Lincoln Park (McGowan South 321D office; 325 lab). Documentation is partial or indirect, so the listing is treated as likely current. Faculty medicinal and chemical-biology research group developing inhibitors and selective substrates for inflammatory caspases (caspase-1, -4, -5). Work combines synthetic organic chemistry, biochemical assays, fluorogenic peptide substrates, and structure–activity relationship (SAR) profiling. Access: 🟡 Yellow — Needs an appointment or affiliation.

Summary 🟡 ~

  • College / school: College of Science and Health
  • Sub-unit: Chemistry and Biochemistry
  • Campus/Location: Lincoln Park (McGowan South 321D office; 325 lab)
  • Last Verified: May 30, 2026

Access (availability): 🟢 Green — open or routine · 🟡 Yellow — appointment or affiliation · 🔴 Red — restricted · ⚪/⚫ White/Black — not yet classified

Verification: ✓ confirmed · ~ likely · ? needs review · ✕ archived

Description & capabilities

Faculty medicinal and chemical-biology research group developing inhibitors and selective substrates for inflammatory caspases (caspase-1, -4, -5). Work combines synthetic organic chemistry, biochemical assays, fluorogenic peptide substrates, and structure–activity relationship (SAR) profiling.

Access status

  • Access: 🟡 Yellow — Needs an appointment or affiliation
  • Rationale: Karver Lab faculty profile documents McGowan South office and lab rooms; access through chemistry research affiliation.
  • Access URL: www.depaul.edu/faculty/caitlin-e-karver
  • Contact name: Caitlin E. Karver
  • Contact email: ckarver@depaul.edu
  • Verification date: 2026-05-30
  • Source URLs:
  • www.depaul.edu/faculty/caitlin-e-karver

Verification

  • Status: ~ Likely current
  • Rationale: Faculty-profile-anchored Karver Lab with published office/lab rooms and research focus.
  • Last verified: 2026-05-30
  • Evidence:
  • DePaul faculty profile McGowan South 321D/325 and caspase research program

Equipment

Find this resource from the Equipment catalog or site search by instrument or lab name.

Category Specific equipment
Spectrometers Fluorogenic peptide-substrate assays; FRET-based caspase activity monitoring
Lab sample processing Small-molecule synthesis and biochemical caspase inhibitor screening (McGowan South 325)

Source: Karver DePaul faculty profile (May 2026). Last verified: July 29, 2026.

Contacts (resource-level)

Last verified: May 30, 2026.

People & contacts

Named contacts when publicly documented.

Source URL

Official links and email are listed under Contacts above.

Documented Relationships

Medicinal chemistry research group; joint FRET-substrate projects with Southern Lab ([CSH-018](../CSH/CSH-018.md)) — documented in PUB-013, Design and Application of a Fluorogenic Assay for Monitoring Inflammatory Caspase Activity (DOI); uses shared McGowan instrumentation (CSH-001). Department chair also directs CSH-001/CSH-002/CSH-003 administration.

Documented connections

Generated from documented publication and people connections. Superscript numbers open Sources below. Multiple sources on one claim are grouped as 1,4. Grant links are listed on publication and grant pages.

Publications

People on linked publications

Sources

  1. Karver faculty profile states fluorogenic FRET-based assay developed in Karver lab in collaboration with Carey Southern; McGowan South 325 lab on profile. Archived source retained by Resource Map maintainers. View current source
  2. Karver faculty profile lists Kyle A. Grice and Caitlin E. Karver as coauthors, J. Mol. Struct. 2024; documents Grice↔Karver collaboration (no explicit facility acknowledgment). Archived source retained by Resource Map maintainers. View current source

Notes

Faculty-profile-anchored lab resource (May 2026).