Connolly Lab (Herpesvirus Entry & Membrane Fusion) (CSH-020)
Summary 🟡 ✓
- Owner Unit: College of Science and Health
- Sub-unit: Health Sciences / Biological Sciences
- Content Type: laboratory
- Campus/Location: Lincoln Park
- Last Verified: June 14, 2026
Description & capabilities
The Connolly Lab studies how herpesviruses achieve the first step of infection — entry into a host cell. Research focuses on how viral surface glycoproteins interact with each other and with cellular factors to trigger fusion of the viral and cellular membranes, and on how the viral fusion protein physically refolds to drive membrane merger. The lab uses molecular biology, microbiology, cell biology, and protein-biochemistry approaches, using herpes simplex virus type 1 (HSV-1) as a model. The work is supported by NIH funding.
Access status
- Level: yellow (
Negotiated Access) - Rationale: Academic research lab represented by a faculty profile with published contact; access is by arrangement with the PI.
- Access URL: www.depaul.edu/faculty/sarah-connolly
- Contact name: Sarah Connolly
- Contact email: sarah.connolly@depaul.edu
- Verification date: 2026-06-14
- Source URLs:
- www.depaul.edu/faculty/sarah-connolly
Verification
- Status: confirmed (
✓) - Confidence: 88/100
- Rationale: Official DePaul faculty page describes the Connolly lab's research program; corroborated by DePaul Find-an-Expert and NIH-funded peer-reviewed publications.
- Last verified: 2026-06-14
- Evidence:
- Faculty page www.depaul.edu/faculty/sarah-connolly ("The goal of the Connolly lab…")
- Find an Expert resources.depaul.edu/newsroom/find-an-expert/Pages/default.aspx
- NIH-funded publications (PubMed 33087881; R01 AI067048/AI076183/AI137267)
Equipment
Molecular biology and virology lab; no dedicated public hardware inventory.
Last verified: May 28, 2026.
Contacts (resource-level)
- Website: Sarah Connolly (DePaul Faculty)
- Email: Sarah Connolly
People & contacts
Named contacts from the people registry when publicly documented.
- Sarah Connolly (Faculty lead) — sarah.connolly@depaul.edu · Profile
Source URL
Official links and email are listed under Contacts above.
Documented Relationships
Led by Sarah Connolly, Professor and Chair of Health Sciences (joint appointment with Biological Sciences). NIH-funded HSV entry research; grant GRA-279 (NIH, "Mechanism of herpes simplex virus (HSV) induced membrane fusion") linked to this lab.
Linked Relationship IDs
None yet.
Notes
PI Sarah Connolly (PER-119). Promoted from candidate RC-006 on 2026-06-14 via institutional web evidence (packet 2026-06-14-hard-tech-candidate-web-discovery).